Close
  Indian J Med Microbiol
 

Figure 4: Direct and indirect basal ganglia pathway involved in saccade generation. Voluntary saccades are triggered by excitatory projections to the caudate from the frontal cortex via the indirect pathway. The caudate nucleus, in turn, phasically inhibits the substantia nigra, which tonically inhibits the superior colliculus. Therefore, excitation of the caudate nucleus could lead to disinhibition of the superior colliculus and facilitate the generation of voluntary saccades. Saccade initiation may be mediated by attenuating the inhibitory pathway to the superior colliculus via the direct pathway of the basal ganglia.

Figure 4: Direct and indirect basal ganglia pathway involved in saccade generation. Voluntary saccades are triggered by excitatory projections to the caudate from the frontal cortex via the indirect pathway. The caudate nucleus, in turn, phasically inhibits the substantia nigra, which tonically inhibits the superior colliculus. Therefore, excitation of the caudate nucleus could lead to disinhibition of the superior colliculus and facilitate the generation of voluntary saccades. Saccade initiation may be mediated by attenuating the inhibitory pathway to the superior colliculus via the direct pathway of the basal ganglia.