Annals of Movement Disorders

CASE REPORTS
Year
: 2020  |  Volume : 3  |  Issue : 2  |  Page : 112--114

Immune-mediated chorea in a patient with kappa light-chain monoclonal gammopathy


Amrita J Gotur1, Roopa Rajan1, Rishi Dhawan2, Ajay Garg3 
1 Department of Neurology, All India Institute of Medical Sciences, New Delhi, India
2 Department of Hematology, All India Institute of Medical Sciences, New Delhi, India
3 Department of Neuroradiology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Roopa Rajan
Department of Neurology, Neurosciences Center, All India Institute of Medical Sciences, New Delhi.
India

The objective of this paper was to report on a case of steroid-responsive chorea in a patient with κ light-chain monoclonal gammopathy. In addition to subacute-onset generalized chorea, evidence of peripheral neuropathy in this elderly gentleman led us to investigate for paraproteinemia. We treated the patient with intravenous steroids in view of elevated κ light-chain assay and bone marrow biopsy, suggestive of monoclonal gammopathy of undetermined significance. There was a remarkable improvement of paresthesias and chorea at 6 months follow-up with no evidence of evolution to malignancy at 1 year. Autoimmune chorea is a treatable condition if identified and treated timely.


How to cite this article:
Gotur AJ, Rajan R, Dhawan R, Garg A. Immune-mediated chorea in a patient with kappa light-chain monoclonal gammopathy.Ann Mov Disord 2020;3:112-114


How to cite this URL:
Gotur AJ, Rajan R, Dhawan R, Garg A. Immune-mediated chorea in a patient with kappa light-chain monoclonal gammopathy. Ann Mov Disord [serial online] 2020 [cited 2022 Sep 27 ];3:112-114
Available from: https://www.aomd.in/article.asp?issn=2590-3446;year=2020;volume=3;issue=2;spage=112;epage=114;aulast=Gotur;type=0