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Faciobrachial dystonic seizure-like events in a patient with subacute sclerosing panencephalitis
Vikram V Holla1, Sudhakar Pushpa Chaithra1, Shweta Prasad2, Nitish Kamble1, Pramod Kumar Pal1, Ravi Yadav1
1 Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India
2 Clinical Neurosciences and Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India
Correspondence Address:
Ravi Yadav,
Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru - 560029, Karnataka
India
 Source of Support: None, Conflict of Interest: None
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Faciobrachial dystonic seizure is a distinctive phenomenology that is considered pathognomonic of leucine-rich glioma-inactivated protein 1 (LGI1) antibody-associated autoimmune limbic encephalitis. However, similar phenomenology has been described with other neurological disorders as well. Here, we report the case of a 26-year-old man with subacute sclerosing panencephalitis who presented with multiple episodes of involuntary movements resembling faciobrachial dystonic seizure. Serum and cerebrospinal fluid autoimmune encephalitis panel, including leucine-rich glioma-inactivated protein 1 antibody, were negative. Classical periodic stereotypical slow wave discharges on the electroencephalogram and raised measles antibody titre in cerebrospinal fluid confirmed the diagnosis of subacute sclerosing panencephalitis. |
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