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CASE REPORT
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Hemifacial spasm responsive to single low-dose abobotulinumtoxin A in a patient with relapsing-remitting multiple sclerosis: A case report


1 The Neuroscience Institute, Department of Neuroscience and Behavioral Medicine, University of Santo Tomas Hospital, Manila, Philippines
2 The Neuroscience Institute, Department of Neuroscience and Behavioral Medicine, University of Santo Tomas Hospital; The Research Center for Health Sciences, Faculty of Medicine and Surgery, University of Santo Tomas, Manila, Philippines

Correspondence Address:
Julie Ann Kristy L Torres,
Department of Neuroscience and Behavioral Medicine, University of Santo Tomas Hospital, Manila - 1015, Metro Manila
Philippines
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Source of Support: None, Conflict of Interest: None

Hemifacial spasm (HFS) is a movement disorder characterized by involuntary twitching of the facial muscles of one side of the face. Here, we report the case of a 31-year-old woman with relapsingremitting multiple sclerosis who presented with left-sided HFS while receiving interferon beta. Despite immunosuppressive medications and clonazepam, only a partial response was documented. Near complete resolution of HFS was achieved 6 months after a single low dose of abobotulinumtoxin A was injected into the left periocular muscles; no recurrence was observed after 4 years. Botulinum toxin injection for focal dystonia, such as HFS, may lead to long-term symptomatic benefit in patients with multiple sclerosis who have already received optimum medical treatment.


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    -  Torres JA
    -  de Leon MA
    -  Rosales RL
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