| CASE REPORTS |
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| Year : 2021 | Volume
: 4
| Issue : 3 | Page : 153-156 |
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Huntington’s disease presenting as adult-onset tourettism: a case report
Mitesh Chandarana, Udit Saraf, Kalikavil Puthanveedu Divya, Syam Krishnan
Comprehensive Care Centre for Movement Disorders, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India
Correspondence Address:
Dr. Syam Krishnan
Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala.
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/AOMD.AOMD_1_21
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Huntington’s disease (HD) is an autosomal dominant progressive neurodegenerative disease, caused by trinucleotide repeat expansion (CAG) in the Huntingtin gene (HTT) on chromosome 4. It is typically characterized by the combination of chorea with or without other extrapyramidal symptoms, oculomotor abnormalities, cognitive decline, and neuropsychiatric manifestations. However, HD consists of considerable phenotypic variability. Though chorea is the most common extrapyramidal manifestation, it is also associated with other movement disorders such as dystonia, myoclonus, tics, parkinsonism, and ataxia. |
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