CASE REPORTS |
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Year : 2020 | Volume
: 3
| Issue : 2 | Page : 112-114 |
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Immune-mediated chorea in a patient with kappa light-chain monoclonal gammopathy
Amrita J Gotur1, Roopa Rajan1, Rishi Dhawan2, Ajay Garg3
1 Department of Neurology, All India Institute of Medical Sciences, New Delhi, India 2 Department of Hematology, All India Institute of Medical Sciences, New Delhi, India 3 Department of Neuroradiology, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Dr. Roopa Rajan Department of Neurology, Neurosciences Center, All India Institute of Medical Sciences, New Delhi. India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/AOMD.AOMD_13_20
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The objective of this paper was to report on a case of steroid-responsive chorea in a patient with κ light-chain monoclonal gammopathy. In addition to subacute-onset generalized chorea, evidence of peripheral neuropathy in this elderly gentleman led us to investigate for paraproteinemia. We treated the patient with intravenous steroids in view of elevated κ light-chain assay and bone marrow biopsy, suggestive of monoclonal gammopathy of undetermined significance. There was a remarkable improvement of paresthesias and chorea at 6 months follow-up with no evidence of evolution to malignancy at 1 year. Autoimmune chorea is a treatable condition if identified and treated timely. |
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